Description
AICAR Liquid Research Overview
Disclaimer: The compounds described on this page are intended for laboratory research use only and are not approved for human consumption.
Overview of AICAR
AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is an adenosine analog that is studied to focus on cellular energy regulation in research models. It activates AMPK (AMP-activated protein kinase), which is a key metabolic regulator. This activation can be beneficial for cells to manage energy use in research models. Researchers study AICAR to observe processes such as lipid metabolism, fat oxidation, and muscle energy efficiency in test models.
AICAR can have its effects on stem cell behavior, inflammation pathways, and metabolic functions in research. Studies show how it affects osteogenic and astroglial differentiation, insulin signaling, and responses to metabolic stress in test models. However, all these findings remain preliminary, and AICAR is studied for research purposes only.
| Section | Details |
|---|---|
| CAS Number | 2627‑69‑2 |
| Molar Mass | 258.2 g/mol |
| Chemical Formula | C₉H₁₄N₄O₅ |
| IUPAC Name | [(2R,3S,4R,5R)-5-(5-amino-4-carbamoylimidazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate [R] |
| Synonyms | AICA ribonucleotide, Z-nucleotide, AICA Ribotide, AICA-ribonucleotide, F0X88YW0YK |
| Ingredients / Composition | The key ingredient in AICAR liquid is AICAR with a purity of 99.8%. |
| Shelf Life | 2 years |
| Storage Instructions | Store AICAR at a temperature of –20 °C. |
| Disclaimer | AICAR is not approved for human use. It is available for research purposes only. |
AICAR’s Mechanism of Action in Research Models
AICAR functions by activating AMP-activated protein kinase (AMPK). AICAR is converted into ZMP inside cells. It mimics AMP, which is the natural activator of AMPK. When AMPK is activated, it affects how cells produce energy and manage fat in research models.
Why Consider AICAR Liquid for Research?
Researchers may consider AICAR Liquid based on its intended research application, available specifications, and supporting documentation.
- Vendor-reported purity of AICAR Liquid: 99.8%. Review the vendor’s certificate of analysis for the batch.
- The assay result of AICAR Liquid is measured at 98.9%. This shows consistent potency.
- The appearance of the AICAR Liquid is a clear, colorless to light yellow liquid. This product passes visual inspection standards.
- The microbial testing shows no growth detected, and endotoxin levels remain low at <0.5 EU/mL. This is well within the ≤5 EU/mL limit.
- The heavy metals in this product are measured at <5 ppm, which meets the acceptable ≤10 ppm specification.
- AICAR Liquid comes with a complete Certificate of Analysis for research validation.
For queries, complaints, or support, please contact help@ironmountainlabz.com
Frequently Asked Questions
Is AICAR FDA-approved?
AICAR is not FDA-approved for human consumption. It is an experimental compound, and credible sources note that it is not authorized for therapeutic applications. This product is available for research purposes only.
What are the reported effects of AICAR in research?
AICAR leads to a variety of metabolic effects in research models. It is noted to increase glucose uptake and fatty-acid oxidation and reduce fat build-up in the liver in research models.
What is the half-life of AICAR in research models?
The half-life of AICAR is short in research. Its elimination half-life is reported to be about 2 hours in preclinical studies.
Is AICAR safe in research?
AICAR is considered safe when it is used at controlled doses in research models. It has benefits like improved metabolism and muscle function in test models. High doses of AICAR can lead to liver stress in some models.
Where can readers find vendor information for AICAR Liquid?
Iron Mountain Labz provides research information and affiliate purchasing pathways but does not directly sell, manufacture, warehouse, or ship AICAR Liquid. Readers should assess third-party suppliers independently and review available identity, purity, and batch-testing documentation.
IML Affiliate Disclosure
Some links on IML may connect readers with third-party suppliers through affiliate arrangements. IML may receive compensation from qualifying transactions at no additional cost to the reader, but the third-party supplier remains responsible for the actual sale, fulfillment, and product documentation.
