Description
5-Amino-1MQ Research Overview
5-Amino-1MQ is a synthetic small molecule studied as an inhibitor of nicotinamide N-methyltransferase (NNMT). Despite often appearing alongside research peptides, it is not a peptide.
Its primary research interest comes from the role of NNMT in cellular methylation and metabolic processes, particularly within adipose tissue.
How It Works
NNMT participates in the metabolism of nicotinamide and methyl donors. Experimental inhibition of this enzyme has been investigated for its potential effects on NAD+-related metabolism, lipid handling, and adipocyte biology.
Research involving 5-Amino-1MQ remains predominantly preclinical, with no established human therapeutic evidence identified for weight loss.
POTENTIAL RESEARCH INTEREST
- NNMT pathway research: The compound provides a tool for examining the biological consequences of reducing NNMT activity.
- Adipose biology: Animal and cellular research has explored its effects on fat-cell metabolism and lipid accumulation.
- NAD+-related research: NNMT inhibition is being studied in relation to pathways connected with nicotinamide and NAD+ metabolism.
- Metabolic research: Mouse studies have reported changes in body weight and metabolic markers, although these findings cannot be assumed to translate to humans.
Dosage
No medically established human dosage exists for 5-Amino-1MQ. Animal-study quantities should not be converted into human dosing recommendations.
Side Effects
Human safety data are not established. The absence of confirmed human adverse-event data should not be interpreted as proof of safety.
Handling & Safety
Handle as an investigational laboratory chemical using suitable gloves, eye protection, and controlled working practices. Avoid ingestion, inhalation, and unnecessary skin exposure.
Where to Buy 5-Amino-1MQ
IML does not directly sell 5-Amino-1MQ. Where affiliate links are available, they may redirect to independent research suppliers. Verify the exact chemical form, identity, batch documentation, and research-use labeling before making a purchase.
IML Affiliate Disclosure
IronMountainLabz may earn a commission from selected third-party links. Such compensation does not mean that IML owns, manufactures, stores, or supplies the referenced material.
References
- PubChem. NNMTi / 5-Amino-1-methylquinolinium iodide. CID 66522933. PubChem record




