Sildenafil + Dapoxetine Tablets

Description

Sildenafil + Dapoxetine

Sildenafil + Dapoxetine Tablets are offered as 100mg Sildenafil per tablet and 60mg Dapoxetine per tablet, totaling 160mg per tablet.

Sildenafil

Sildenafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The prostate is one of the areas where this enzyme works. Sildenafil is also used in both men and women to treat the symptoms of pulmonary arterial hypertension. This is a type of high blood pressure that is prevalent between the lungs and heart. When there is high blood pressure in the lungs, the heart must work harder to pump enough blood through the lungs. Sildenafil works on the PDE5 enzyme in the lungs to effectively relax the blood vessels. This will increase the supply of blood to the lungs and reduce the workload of the heart. A recent study found that short‐term treatment with sildenafil reduces skeletal muscle fatigue and stimulates skeletal muscle protein synthesis while altering muscle protein expression and nitrosylation. These findings provide evidence that sildenafil can remodel the human skeletal muscle in a more functionally adaptive manner.

 

Sildenafil
CAS Number	171599-83-0
Molar Mass	666.7 g/mol
Chemical Structure	C28H38N6O11S
IUPAC Name	5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one;2-hydroxypropane-1,2,3-tricarboxylic acid

Dapoxetine

Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) medicine that has especially been developed for the treatment of premature ejaculation. Dapoxetine is an SSRI that may prolong intravaginal latency time from less than a minute to an average of over 3 minutes. The mechanism may involve increased serotonin to the brain stem, modulating pudendal nerve activity via descending pathways.

Dapoxetine
CAS Number	12993-8-20-1
Molar Mass	305,413g/mol
Chemical Structure	C21H23NO
IUPAC Name	(1S)-N,N-dimethyl-3-naphthalen-1-yloxy-1-phenylpropan-1-amine