Description
GHRP-2 (Growth Hormone Releasing Peptide-2) 10mg Research Overview
Disclaimer: The compounds described on this page are intended for laboratory research use only and are not approved for human consumption.
Overview of GHRP-2
GHRP-2 is a synthetic hexapeptide supplied as a 10mg lyophilized powder (catalog code GHRP2-10). Also known by its pharmaceutical name pralmorelin, it is a growth hormone secretagogue (GHS) studied for stimulating pituitary GH release via the ghrelin receptor (GHS-R1a). It is approved in Japan as a diagnostic agent for growth hormone deficiency, but it is not FDA-approved for any use in the United States and is not a dietary supplement.
Regulatory Note (2026): GHRP-2 is explicitly named on the 2026 WADA Prohibited List under Section S2.2.4 (Growth Hormone Releasing Factors GH-Releasing Peptides), prohibited at all times, in and out of competition, for any tested athlete. It is not currently part of the FDA’s July 2026 PCAC compounding review batch (which covers BPC-157, TB-500, KPV, and MOTS-c); GHRP-2 remains an unregulated research chemical in the US outside of any 503A pathway.
GHRP-2
GHRP-2 (D-Ala-D-2Nal-Ala-Trp-D-Phe-Lys-NH2) is a synthetic hexapeptide containing unnatural D-amino acids that confer resistance to enzymatic degradation. It is studied as a ghrelin receptor (GHS-R1a) agonist, the same receptor pathway used by Ipamorelin and GHRP-6, though GHRP-2 is generally reported as more potent for peak GH output while producing a moderate, rather than pronounced, secondary effect on cortisol and prolactin. Not a SARM; not a GHRH analogue.
GHRP-2 Chemical Properties
| Section | Details |
| CAS Number | 158861-67-7 |
| PubChem CID | 6918245 |
| Molar Mass | ~817.97 g/mol |
| Chemical Formula | C45H55N9O6 |
| Sequence | D-Ala-D-2Nal-Ala-Trp-D-Phe-Lys-NH2 |
| Synonyms | Pralmorelin, KP-102 |
| Chemical Class | Synthetic hexapeptide growth hormone secretagogue (ghrelin receptor agonist) |
| Physical Form | Lyophilized powder |
| Purity | Verify per Certificate of Analysis |
| Storage | -20°C; protect from light and moisture |
| Shelf Life | Verify per Certificate of Analysis |
| Regulatory Status | Research chemical in the US; approved in Japan as a GH-deficiency diagnostic (pralmorelin); not FDA-approved |
| WADA Status | Prohibited at all times S2.2.4 (Growth Hormone Releasing Factors / GHRPs), explicitly named |
| Compound’s Disclaimer | Not evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease. For laboratory research use by qualified personnel only. |
GHRP-2’s Mechanism of Action
GHRP-2 is studied for binding the ghrelin receptor (GHS-R1a) on pituitary somatotroph cells, triggering pulsatile release of growth hormone independent of the GHRH-receptor pathway used by compounds like CJC-1295. This GH release is reported to drive downstream increases in IGF-1, with secondary, comparatively moderate effects on cortisol and prolactin release relative to older GHRPs like GHRP-6. Validated LC-MS/MS methods exist for detecting GHRP-2 and its metabolites in human urine, reflecting its established use in anti-doping laboratories.
Risk & Handling
- Handle with gloves and eye protection; avoid inhaling powder during weighing or reconstitution.
- Keep frozen (-20°C) and protected from light and moisture until needed.
- Only trained personnel should prepare or dose this product.
Why Consider GHRP-2 for Research?
- Purity confirmed per lot, with method specified on Certificate of Analysis.
- Identity confirmed per lot; structural data available on COA.
- Certificate of Analysis available on request per lot.
- Expert assistance technical questions and compliance guidance.
- Contact: help@ironmountainlabz.com
Frequently Asked Questions
What is the regulatory status of GHRP-2?
Yes, as a research chemical it’s not FDA-approved as a drug in the US (though it is approved in Japan for a diagnostic use), so it’s sold for laboratory research use, not as a finished consumer product.
Is GHRP-2 banned for athletes?
Yes, unambiguously. It’s explicitly named on the World Anti-Doping Agency’s Prohibited List, banned at all times for any tested athlete there’s no in-competition-only loophole and no realistic path to a therapeutic use exemption for performance purposes.
What exactly is in this 10mg vial?
One compound: GHRP-2, a lab-made six-amino-acid peptide (also called pralmorelin), supplied as a freeze-dried powder.
What is GHRP-2 typically studied for?
Triggering the pituitary gland to release growth hormone, through a pathway separate from the one GHRH-type peptides use. It’s one of several compounds in the “growth hormone secretagogue” family, alongside things like Ipamorelin and GHRP-6.
How should this be stored and handled?
Keep it frozen (-20°C), away from light and moisture. Use gloves and eye protection when handling, and avoid inhaling the powder during weighing or reconstitution.
References
- National Center for Biotechnology Information (NCBI). PubChem CID 6918245 (GHRP-2 / Pralmorelin). National Institutes of Health. https://pubchem.ncbi.nlm.nih.gov/compound/6918245
- Bowers CY. Growth hormone-releasing peptide (GHRP). Cell Mol Life Sci. 1998;54(12):1316-1329. PMID: 9893710. https://pubmed.ncbi.nlm.nih.gov/9893710/
- Okano M, Sato M, Ikekita A, Kageyama S. Determination of growth hormone secretagogue pralmorelin (GHRP-2) and its metabolite in human urine by liquid chromatography/electrospray ionization tandem mass spectrometry. Rapid Commun Mass Spectrom. 2010;24(14):2046-2056. PMID: 20552695. https://pubmed.ncbi.nlm.nih.gov/20552695/
- World Anti-Doping Agency. The 2026 Prohibited List International Standard, Section S2.2.4. https://www.wada-ama.org/en/prohibited-list
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