Description
Semax Nasal Spray
Disclaimer: All Iron Mountain Labz products are only intended for laboratory research use and are not approved for human consumption.
Overview of Semax
Semax is a synthetic heptapeptide that is derived from the adrenocorticotropic hormone (ACTH) fragment (Met-Glu-His-Phe-Pro-Gly-Pro). It is modified with a Pro-Gly-Pro sequence to increase stability in research. This compound belongs to a class of nootropic peptides.
Mechanistically, Semax shows multifaceted activity by modulating neurochemical pathways involved in stress response, neurotransmission, and neuroprotection. Research findings show that Semax upregulates brain-derived neurotrophic factor (BDNF). This supports synaptic plasticity and neuronal survival in research models.
| Section | Details |
| CAS Number | 80714-61-0 ® |
| Molar Mass | 813.929 g/mol |
| Chemical Formula | C37H51N9O10S |
| IUPAC Name | (2S)-1-[2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-4-carboxybutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carboxylic acid |
| Synonyms | ACTH (4-7), Pro-Gly-Pro-, I5FAL2585H, Pro-gly-pro-acth (4-7), MEHFPGP |
| Ingredients / Composition | Semax Nasal Spray contains Semax with 98.8% purity. |
| Shelf Life | 36 months |
| Storage Instructions | Store Semax Nasal Spray in a cool and dry place at 2–8°C. |
| Disclaimer | Semax Nasal Spray is not approved for human use. It is legal for research purposes only. |
Why buy Semax Nasal Spray from Iron Mountain Labz?
Iron Mountain Labz is a preferred choice for researchers to buy Semax Nasal Spray due to the following reasons.
- At Iron Mountain Labz, Semax Nasal Spray is tested with HPLC and confirmed at 99.8% purity.
- The assay result of this product meets research-grade standards at 98.9%.
- The endotoxin levels were measured at <0.5 EU/mL, which is below the specified limit.
- The pH value of this product was tested at 7.0, which is within the standard limit of 6.5–7.5.
- A Certificate of Analysis (COA) is provided for verification.
Note: The Peptide Nasal Spray category at Iron Mountain Labz also includes Selank Nasal Spray and TB-500 Nasal Spray. These peptide nasal sprays are studied for their effects on neurological and physiological functions in research models.
Frequently Asked Questions
Is Semax Nasal Spray legal?
Semax Nasal Spray is not approved by the FDA for medical use in the United States. Its legal status is limited to research purposes only.
What is the peptide structure of Semax?
Semax has an amino acid sequence Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP). It has a molecular weight of approximately 813.929 g/mol and is non-glycosylated.
What mechanisms of action have been observed for Semax in preclinical research?
Preclinical studies show that Semax upregulates brain-derived neurotrophic factor (BDNF) and its receptor TrkB to increase neuroplasticity and learning capacity. It also reduces the expression of inflammatory genes and protects neurons under oxidative stress or hypoxia in research. It modulates dopaminergic and serotonergic pathways in ischemia models.
What results have researchers noted with Semax?
Researchers have observed that Semax upregulates brain-derived neurotrophic factor (BDNF) in research models. This activity supports neuroplasticity and neuronal survival. It has shown neuroprotective effects under oxidative stress and hypoxia. It also modulates dopamine and serotonin pathways in experimental models.
What storage conditions are recommended for Semax peptides?
Lyophilized (freeze-dried) Semax should be stored desiccated (dry) at around −18 °C to −20 °C for long-term stability. After reconstitution, it should be kept at about 4 °C and used within a limited timeframe in research.
What are the differences between Semax and traditional nootropics?
Semax is a peptide analog derived from ACTH(4-10) with strong neurotrophic and neuroprotective effects. It tends to act by upregulating growth factors like BDNF to reduce inflammation and oxidative stress in research models.
What is the best place to buy Semax Nasal Spray online for research use?
Semax Nasal Spray is available through many online stores. Iron Mountain Labz is one of the best options for getting peptide products for research purposes. Our products align with regulatory standards, and each comes with a COA for ingredient verification.






Gordon Vega –
A secret weapon for your brain, keeping you sharp and alert throughout the day
Syed Rivers –
My mental clarity and agility greatly improved since I’ve been using this. Love the variety as well.
Zach Cardenas –
Mental clarity and alertness are much better, with literally zero side effects. Thought I would get the jitters, but I’m all good and will definitely get this again in the future. Recommending this to some friends as well.
Vinnie Frazier –
Mental clarity definitely improved with this. Looking forward to researching some other products soon!
Solomon Carpenter –
Handy little cognitive enhancer! Like it a lot
Solomon Carpenter –
Handy little cognitive enhancer! Like it a lot
Cameron Lucas –
Dramatically enhanced my focus
Cameron Lucas –
Dramatically enhanced my focus
Ryan Delacruz –
Hard to believe that this is safe lol. But I’m getting good results without any side effects and naturally, its also super convenient so you simply can’t go wrong with this
Ryan Delacruz –
Hard to believe that this is safe lol. But I’m getting good results without any side effects and naturally, its also super convenient so you simply can’t go wrong with this
Harold Mullins –
Mental performance and memory definitely increased while researching with this. This is a very good product overall in my opinion and I’ll probably stick to this for a while; new order coming in hot!
Harold Mullins –
Mental performance and memory definitely increased while researching with this. This is a very good product overall in my opinion and I’ll probably stick to this for a while; new order coming in hot!
Chanel Castro –
One of the best I’ve tried. Does the job.
Forest –
Incredible! I’m feeling so much better already.